Clinical and hemtaologic fluctuations in hairy-cell leukemia: a sequential surface-marker analysis
نویسندگان
چکیده
منابع مشابه
Clinical and hemtaologic fluctuations in hairy-cell leukemia: a sequential surface-marker analysis.
A sequential surface-marker study was performed on the peripheral blood of ten patients with hairy-cell leukemia. All patients were studied for at least a year, and it was shown that changes in the predominant cell population occurred in six and that these changes were not related to variations in the absolute leukocyte count. In four cases, no major change in peripheral populations was observe...
متن کاملHairy Cell Leukemia in a Young Male: An Unusual Presentation
Dear Editor-in-Chief A 28 yr male was presented in October 2015 at Medicine Outpatient Department, Safdarjung Hospital, New Delhi- India with generalized weakness, fever and cough for preceding 15 days. Clinicoradiologic examination revealed pallor, firm, non-tender splenomegaly measuring 13.7 cm and hepatomegaly (liver span - 16.9 cm). However, no lymphadenopathy was found.
متن کاملSoluble CD22 as a tumor marker for hairy cell leukemia.
CD22 is an important immunotherapeutic target on B-cell malignancies, particularly hairy cell leukemia (HCL), but its soluble extracellular domain, sCD22, has not yet been reported in the blood. By immunoaffinity and enzyme-linked immunosorbent assay techniques using anti-CD22 monoclonal antibodies, we identified the 100-kDa extracellular domain of CD22 and an 80-kDa processed form in serum of ...
متن کاملCLINICAL TRIALS AND OBSERVATIONS Soluble CD22 as a tumor marker for hairy cell leukemia
CD22 is an important immunotherapeutic target on B-cell malignancies, particularly hairy cell leukemia (HCL), but its soluble extracellular domain, sCD22, has not yet been reported in the blood. By immunoaffinity and enzyme-linked immunosorbent assay techniques using anti-CD22 monoclonal antibodies, we identified the 100-kDa extracellular domain of CD22 and an 80-kDa processed form in serum of ...
متن کاملThe clinical evaluation of hairy cell leukemia.
It seems to be well established by now that hairy cell leukemia (HCL) patients in apparent complete remission may harbor residual hairy cells in their bone marrow demonstrable only by immunohistologic and not by routine morphologic Recently, Pangalis et a13,4 and Catovsky et al’ reported splenic infiltration with hairy cells in HCL patients treated with interferona2b who before splenectomy were...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood
سال: 1980
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v55.5.784.784